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Wycalm (Alprazolam)

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Wycalm is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Acalm, Albiz, Alflux, Almac, Alpra, Alpraquil, Alprazan, Altrex, Alzocum, Alzokam, Alzom, Alzopam, Ambutech, Ateez, Balzam, Besquil, Emlol, Erazol, Exprex, Fultop, Golprax, Nitril, Prolam, Sertamax, Sinaday, Somnarest, Tenscure, Tenzorid, Trika, Xanti, Zallpam, Zopain

Similar Products:
Rulide, Plavix, Prandin, Norvasc, Cipro, Microzide, Effexor, Avana, Aceon, Paxil, Binadis, Tenschem, Caduet, Urivate, Septriol, Clotof, Albins,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Wycalm XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Wycalm XR may be habit-forming and should be used only by the person it was prescribed for. Wycalm XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Wycalm extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Wycalm XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Wycalm XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Wycalm XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Wycalm XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Wycalm XR dosage information


If you have been prescribed Wycalm for medical reasons, the best way to avoid a Wycalm overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Wycalm consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Wycalm XR dosage information

Side effects

The most common side effects associated with Wycalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Wycalm if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Wycalm is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Wycalm while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Wycalm is not approved for use by anyone younger than 18 years old.

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Construction of HSP47-shRNA and its impact on HSP47 at cellular level. Using repetitive extragenic palindromic PCR, the isolates could be divided into 4 different clones, with 40 isolates belonging to clone A and the remaining to B, C and D. We performed skin prick tests (SPT) with a panel of common aeroallergens and total serum immunoglobulin (Ig)E and specific IgE tests for CR and HDM on 23 patients with AD and 9 nonatopic control participants. Asthma inhaler adherence determinants in adults: systematic review of observational data. For both conditions, activity began in the posterior occipital and mid-parietal areas. Follicular mantle lymphoma: clinicopathologic and cell proliferation of 11 cases. The expression of carcinoembryonic antigen(CEA) on tumor cells freshly excised from 51 patients with gastric cancer was studied using flow cytometry. We utilized this method to modify the surface property of single conical track-etched nanopores.

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Testicles were discovered within a constricted, subcutaneous space near the inguinal canals. Follow up data were obtained from the charts and from the attending clinician or family physician. Our results lead to novel experimental predictions that unambiguously signal the transition from a Kondo state to an antiferromagnetic spin-singlet state, directly reflecting the physics of the two-impurity Kondo problem. In this observational study, we evaluated coronary flow reserve (CFR) via echocardiography of 95 subjects having a biological parent with type-2 diabetes and 34 healthy volunteers without any biological parent with type-2 diabetes. Total synthesis of the cyanobacterial metabolite largamide B and the disproval of its originally assigned stereochemistry as well as confirmation of the revised stereochemistry are reported. A modified anaerobic digestion process with chemical sludge pre-treatment and its modelling.

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Anticipated postoperative pain may affect procedure choice in patients with pectus excavatum. Whereas none of the strains adhered from water to glass due to electrostatic repulsion, R. RNAs corresponding to rpoB- rpoC1-rpoC2, which encode subunits of a plastid RNA polymerase, and rps16, which encodes a ribosomal protein, reached maximal abundance early in chloroplast development prior to genes encoding subunits of the photosynthetic apparatus (rbcL, atpB, psaA, petB). Genetic results showing allele specific suppression of cdc34 mutations by various Ub derivatives suggested a specific noncovalent interaction between Ub and CDC34. Studies of most of these genes have not yielded clear-cut results yet, but the participation of some of them in the aetiology of autism is possible. cART appears to have no preventive effect on anal cancer, particularly in MSM. Globally, this work highlights the role of higher-order PCM organization in the regulation of centrosome assembly and function. Allenamides as orthogonal handles for selective modification of cysteine in peptides and proteins. The AAPD 2008 Trauma Symposium in perspective: an overview and summary. Chemogenomics in drug discovery: computational methods based on the comparison of binding sites.

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The ribosomal protein L24 gene may have effects on drug resistance mechanisms in hepatocellular carcinoma HepG2 cells. Orientation and three-dimensional organization of actin filaments in dividing cultured cells. Analysis of a series of truncation and alanine scanning mutants reveals that a consensus casein kinase II site followed by 2 leucines near the COOH terminus that has the sequence (-10)DDSDEDLL(-3) is important for receptor function in sorting of lysosomal enzymes. RecA is central to maintaining genome integrity in bacterial cells. Application of CCh to taenia coli induced transient increase in calcium level and contraction followed by sustained and lower calcium level and smaller contraction, and R59022 inhibited the latter responses specifically. Although tobacco smoking and alcohol drinking are well-established risk factors for oral cancer, relatively few studies have addressed the comparative effect of filter versus non-filter cigarettes, the nature of the reduction in risk following cessation, and the joint effects of tobacco and alcohol. The results suggest that the expression of Hb is not directly influenced by O2 usage or availability but is influenced by the availability of ATP in the tissue. Polylysine with cleavable PEGylation and hydrophobic histidylation (mPEG-SS-Lysn-r-Hism) was designed and developed for efficient siRNA delivery and tumor therapy.

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The genetic variations in serotonin-related genes may be associated with antidepressant treatment response in major depressive disorder (MDD). Large scale cultivation of human diploid cells on titanium discs in a special apparatus. Do age and gender influence outcome from mechanical ventilation?. Xenograft experiments confirmed that suppression of tumor growth in vivo occurred in the absence of functional miR-17. These approaches provided great opportunity to understand the breeding value of SHWs for improving grain weight and enhanced our deep understanding on molecular genetics of grain weight in wheat. Furthermore, neuroendocrine and sleep EEG data from the study in healthy subjects indicate a different profile of action for carbamazepine compared to most other antidepressants or antimanic drugs.

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Localization of hydroxyindole-O-methyltransferase in the retina: a re-evaluation. To assess lifetime prevalence of 7 chronic health conditions (CHCs) among a cohort of adults with chronic traumatic spinal cord injury (SCI). Even patients with combined on-treatment residual ADP- and AA-inducible platelet reactivity did not exhibit significantly higher levels of MPA than patients without any on-treatment residual platelet reactivity. With this treatment, hemolysis has stopped, hematuria has disappeared, proteinuria has almost normalized, and creatinine clearance has been stable. Examples are given to demonstrate the application of the terms in the experimental and clinical analysis of cell locomotion.

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A qualitative study using 12 in-depth interviews and 10 focus groups with Maghrebi adults living in Tarragona. There is a large interindividual variation in serum (free) testosterone (FT) levels in men, underlain in part by genetic components. Few previous studies have investigated the inherent topographies of existing breast implants and the surfaces with which body tissue is exposed. This is a standard treatment in the USA and Canada for early onset ischaemic strokes within three hours of the stroke. The aim of the study was to estimate the prevalence of first intercourse at a young age in various birth cohorts of men and to determine any association with later risky behaviour. Effect of fluoride treatment and calcitriol medication cream subsequent placement of cement on enamel microhardness.

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Analysis of the total gangliosides of beige thymus and spleen indicates that there what is levaquin 500 mg used to treat are several possible deletions, but it still not known whether these deletions are related to the natural killer dysfunction in these mice. A rescued female manatee was observed expelling a fetal bone from the vulva. Revision total hip replacement using the cement-in-cement technique for the acetabular component: technique and results for 60 hips. Recent biochemical and molecular-genetic discoveries concerning variations in human mtDNA have suggested a role for mtDNA mutations in a number of human traits and disorders. In vivo gene transfer between interacting human osteosarcoma cell lines is associated with acquisition of enhanced metastatic potential. The consequence of inadequate outpatient management of CIN can be catastrophic. Rectification inversion in oxygen substituted graphyne-graphene-based heterojunctions. Methodology and outcomes of a family medicine research fellowship. Baseline measures included a broad set of risk factors for mortality such as age, sex, heart failure, diabetes, depression, and smoking. Experiments were carried out in five healthy pigs, followed by a clinical investigation of ten patients with subarachnoid hemorrhage.

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The diagnostic method of choice is nuclear scintigraphy, specifically, a heat-damaged red blood cell scan. JcFT was expressed in all tissues of adult plants except young leaves, with the highest expression level in female flowers. Responses of yeast cells to heat applied alone or combined with gamma-rays. During the operation, the heart infarct of the inferior wall had been observed, but finally in the postoperation period the heart efficiency improvement was observed. Colon carcinoma cells blocked in polarization exhibit increased expression of carcinoembryonic antigen. In an attempt to clarify the role of sigma 28 in the expression of lcrD, myfA, and flagellar genes, we cloned, sequenced, and mutagenized the fliA gene encoding the sigma 28 homolog in Y. We report the case of a 54-year-old male with a 2-cm asymptomatic mass overlying the right parotid gland, which was managed by excision of the affected skin, right total parotidectomy, and right neck dissection. Retinoid agonist activities of synthetic geranyl geranoic acid derivatives. Taking the example of the most frequently prescribed corticosteroid nasal sprays containing the active substances budesonide (BNS) or mometasone (MNS), we will show here that the DDD system is not necessarily suitable for tapping economic reserves. Six normal SD rats with sham operation were taken as the normal control group, 24 steptozozin-induced diabetic SD rats were randomly divided into 4 groups, with 6 in each group.

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Through affinity-based genome-wide sequencing and oxidation-assisted base-resolution sequencing methods, 5hmC is found to be dynamically regulated during development, and is enriched mainly in distal regulatory elements in human and mouse embryonic cost of prometrium cells. A novel optimization technique for improving IMRT was assessed and found to be effective and efficient. Activity of endodontic antibacterial agents against selected anaerobic bacteria. When both variables were manipulated in the same condition, but in opposite directions, responding in the constant component usually changed inversely with the change in rate of reinforcement, not the change in reinforcer duration. The use of expected value as an aid to decisions regarding anticoagulation in patients with atrial fibrillation. Photoaffinity labeling of the PI 4-kinases with 8-azido-ATP was specifically prevented with ADP. A 52-year-old man presented with peri-umbilical distension and abdominal pain for 2 weeks. The assessments included: the Structured Clinical Interview for DSM-IV-TR, the Brief Psychiatric Rating Scale (BPRS), the Obsessive-Compulsive Spectrum Self-Report (OBS-SR), for sexual obsession, and the Mood Spectrum-Self Report lifetime version (MOODS-SR).

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